The Siesta Group

Study Experience

Study Expertises

pharma & cro

  • Narcolepsy
  • Primary Insomnia
  • PLMS; Restless Leg Syndrome
  • Sleep Disorders in Neurological Diseases (Alzheimer’s, Parkinson’s)
  • Chronic Obstructive Pulmonary Disease
  • Obstructive Sleep Apnea Syndrome
  • Health Control Studies
  • Daytime Sleep Studies
  • Sleep Psychopharmacology
  • Pharmaco-EEG in Clinical Studies


References to studies conducted or involved in:

Dingemanse J, Dorffner G, Hajak G, Benes H, Danker-Hopfe H, Polo O, Saletu B, Barbanoj MJ, Pillar G, Penzel T, Chiossi E, Hoever P: Proof-of-concept study in primary insomnia patients with almorexant (ACT-078573), a dual orexin receptor antagonist,
Sleep and Biological Rhythms, Worldsleep07 supplement, 2007.

Brisbare-Roch C, Dingemanse J, Koberstein R, Hoever P, Aissaoui H, Flores S, Mueller C, Nayler O, van Gerven J, de Haas SL, Hess P, Qiu C, Buchmann S, Scherz M, Weller T, Fischli W, Clozel M, Jenck F.: Promotion of sleep by targeting the orexin system in rats, dogs and humans. Nat Med. 2007 Feb;13(2):150-5.

Saletu B, Prause W, Anderer P, Mandl M, Aigner M, Mikova O, Saletu-Zyhlarz GM.:

Insomnia in somatoform pain disorder: sleep laboratory studies on differences to controls and acute effects of trazodone, evaluated by the Somnolyzer 24 x 7 and the Siesta database. Neuropsychobiology. 2005;51(3):148-63.

Barbanoj MJ, Clos S, Romero S, Morte A, Giménez S, Lorenzo JL, Luque A, Dal-Ré R.: Sleep laboratory study on single and repeated dose effects of paroxetine, alprazolam and their combination in healthy young volunteers. Neuropsychobiology. 2005;51(3):134-47

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